Source - Immunodb
http://cegg.unige.ch/insecta/immunodb/

CATs: Catalases
Summary

Carolina Barillas Mury 
Laboratory of Malaria and Vector Research, Twinbrook III Facility, NIAID, NIH, USA 

Catalase is a tetrameric enzyme which efficiently converts H2O2 to water and oxygen. Catalase is a single copy gene in Ag (AgCAT1), but a second gene is present in Dm (CG9314). CG9314 mRNAs are present in EST databases, but the predicted enzyme lacks three of the seven heme-binding residues and is probably not active. This is in agreement with the observation that flies in which DmCat is disrupted are extremely weak, lack catalase activity and die soon after enclosion [Griswold et al. 1993]. In contrast, both catalase genes in Aa appear to code for active enzymes.