>Flyb:REL1 Flyb:N10892 CG6667-PB Dorsal (3 transcripts) Dm_Dl 'REL1'
MFPNQNNGAAPGQGPAVDGQQSLNYNGLPAQQQQQLAQSTKNVRKKPYVKITEQPAGKAL 
RFRYECEGRSAGSIPGVNSTPENKTYPTIEIVGYKGRAVVVVSCVTKDTPYRPHPHNLVG 
KEGCKKGVCTLEINSETMRAVFSNLGIQCVKKKDIEAALKAREEIRVDPFKTGFSHRFQP 
SSIDLNSVRLCFQVFMESEQKGRFTSPLPPVVSEPIFDKKAMSDLVICRLCSCSATVFGN 
TQIILLCEKVAKEDISVRFFEEKNGQSVWEAFGDFQHTDVHKQTAITFKTPRYHTLDITE 
PAKVFIQLRRPSDGVTSEALPFEYVPMDSDPAHLRRKRQKTGGDPMHLLLQQQQKQQLQN 
DHQDGRQTNMNCWNTQNIPPIKTEPRDTSPQPFGLSYRAPPELTPSPQPLSPSSNYNHNS 
TPSPYNMASAVTPTNGQQQLMSPNHPQQQQQQQQYGATDLGSNYNPFAQQVLAQQQQHQQ 
QQQQHQHQHQQQHQQQQQQQQQQQQQSLQFHANPFGNPGGNSWESKFSAAAVAAAAATAT 
GAAPANGNSNNLSNLNNPFTMHNLLTSGGGPGNANNLQWNLTTNHLHNQHTLHQQQQLQQ 
QQQQQYDNTAPTNNNANLNNNNNNNNTAGNQADNNGPTLSNLLSFDSGQLVHINSEDQQI 
LRLNSEDLQISNLSIST 

>Flyb:REL2 Flyb:N1432 CG11992-PA Relish (4 transcripts) Dm_Rel 'REL2'
MNMNQYYDLDNGKNVMFMNDASSTSGYSSSTSPNSTNRSFSPAHSPKTMELQTDFANLNL 
PGGNSPHQPPMANSPYQNQLLNNGGICQLGATNLINSTGVSFGVANVTSFGNMYMDHQYF 
VPAPATVPPSQNFGYHQNGLASDGDIKHVPQLRIVEQPVEKFRFRYKSEMHGTHGSLNGA 
NSKRTPKTFPEVTLCNYDGPAVIRCSLFQTNLDSPHSHQLVVRKDDRDVCDPHDLHVSKE 
RGYVAQFINMGIIHTAKKYIFEELCKKKQDRLVFQMNRRELSHKQLQELHQETEREAKDM 
NLNQVRLCFEAFKIEDNGAWVPLAPPVYSNAINNRKSAQTGELRIVRLSKPTGGVMGNDE 
LILLVEKVSKKNIKVRFFEEDEDGETVWEAYAKFRESDVHHQYAIVCQTPPYKDKDVDRE 
VNVYIELIRPSDDERSFPALPFRYKPRSVIVSRKRRRTGSSANSSSSGTESSNNSLDLPK 
TLGLAQPPNGLPNLSQHDQTISEEFGREKHLNEFIASEDFRKLIEHNSSDLEKICQLDMG 
ELQHDGHNRAEVPSHRNRTIKCLDDLFEIYKQDRISPIKISHHKVEKWFIEHALNNYNRD 
TLLHEVISHKKDKLKLAIQTIQVMNYFNLKDVVNSTLNADGDSALHVACQQDRAHYIRPL 
LGMGCNPNLKNNAGNTPLHVAVKEEHLSCVESFLNGVPTVQLDLSLTNDDGLTPLHMAIR 
QNKYDVAKKLISYDRTSISVANTMDGNNALHMAVLEQSVELLVLILDAQNENLTDILQAQ 
NAAGHTPLELAERKANDRVVQLLKNVYPEKGELAMTWIPCKVKEEIDSSSDESSDAGQLE 
IKSEEMDIETKDEDSVELDLSSGPRRQKDESSRDTEMDNNKLQLLLKNKFIYDRLCSLLN 
QPLGHGSDPQDRKWMQLARQTHLKQFAFIWLGAEDLLDHVKRKGASVEFSTFARALQAVD 
PQAYALLVNPT 

>Flyb:REL3 Flyb:N11000 CG6794-PA Dif (2 transcripts) Dm_Dif 'REL1'
MFEEAFGDIQEIINASMELNGGATGGGSVAGAVGGGGAAHHILSQSTSLPVMPSHIPLHL 
QNQNMNQNLPEPSARSGPHLRIVEEPTSNIIRFRYKCEGRTAGSIPGMNSSSETGKTFPT 
IEVCNYDGPVIIVVSCVTSDEPFRQHPHWLVSKEEADACKSGIYQKKLPPEERRLVLQKV 
GIQCAKKLEMRDSLVERERRNIDPFNAKFDHKDQIDKINRYELRLCYQAFITVGNSKVPL 
DPIVSSPIYGKSSELTITRLCSCAATANGGDEIIMLCEKIAKDDIEVRFYETDKDGRETW 
FANAEFQPTDVFKQMAIAFKTPRYRNTEITQSVNVELKLVRPSDGATSAPLPFEYYPNPE 
LLTKHNRRVAQKTVESLKRSLMSTNLHPSKQVKTSSQYTIFSKPQIATTTPQTQVSPGMP 
LMFPGGSPNFVQDIKMENGFMDVDSQSSQCPSVERNFASPRSNCSTVDSIPPMQMGQNQT 
HLYLPDATNFTFNGNFASPSSNCSTVDSIPPFQIGQRNNHMYLPENSNFPVNGCSPTHFS 
GGSMTPINNNNNVLINNNNNDFLSQKMSAISIPPQGNFGIKQVYQQTQQFLPQLQPESIP 
YLAQSHPEQSQYQQQQQPQEQQPPADEPTQSFSDLISSSIGMAPIDTSELIQDIEAELNS 
LGIQPFK 

>Agam:REL1 Agam:N16239 ENSANGG00000008612 ENSANGP00000011101 REL1 Ag_REL1 'REL1'
MAGYVNGADAAFLPIEGILGESDLLDDIIHVIGKDIREEMPPVPNQRPYVEITEQPHPKA 
LRFRYECEGRSAGSIPGVNTTAEQKTFPSIQVHGYRGRAVVVVSCVTKEGPEHKPHPHNL 
VGKEGCKKGVCTVEINSTTMSYTFNNLGIQCVKKKDVEEALRLRQEIRVDPFRTGFGHAK 
EPGSIDLNAVRLCFQVFLEGQQRGRFTEPLTPVVSDIIYDKKAMSDLIICRLSDCTAPVS 
GGKEIILLCEKVVKEDIKVRFFEKKGNATVWENYAEFSHTDVHKQVAISFRTPPYRTIDI 
SDPVRVFVQLERPSDNTYSEARDFQFIPLDTVDLRRKRQKLTGSSNVFLPVVTAPLPGPS 
PPSSLGMPGNIPNLSQLDATGGQSASTSGLPRGIYTYHNASAFQQMPKEEIKNEPGDSPS 
HNPSNQYQLQPMQPMFTAQSTSPGPDRSPATLTPSPGIGGPISPLDPGNVTPTPPAYTTL 
GGTGGTMGNLFGQFGTGFSNAATQPNASVPMFETNLPGPSNGWVQPVPSHTQNGPSQPQP 
QQQNPFNLLNFGTLPLATGDPLMAMSTANTNNQPNVGPPSLGSDFYMNLDLANLDPVFNS 
SELRSVLGSLSTTDLNRLEQTANMQTSGGNYQQHSASNQQQAIKALLATQQLQQQQQQQQ 
QQQQQQQQGQTGQADRIDNDEDLTDSFTKLSTNDLN 

>Agam:REL2 Agam:N15536 ENSANGG00000017745 (2 transcripts, Q6V2E3_ANOGA has inhibitor) REL2 Ag_REL2 'REL2'
MSTLLNLDSYRHELYEQQQLLGTSPIQYTVLSMDTPSPSSSSAAAAVVSVGEFTLGPGRT 
YASALSPSSSSASPSSPSSVASPNSRASNMSPESSASDQSAAYTLQNLNLSSSAGTMNYP 
GMGYQQQQQQQQQQQQHHQHQQLQQQQHHYYTPQLLNLDQEQLQTQTFTYVTSSNEAFAA 
PEPNYSEPHLVILEQPVDKFRFRYQSEMHGTHGSLMGSRTEKSKKTFPTVELRGYGGEAK 
VRCSLYQVDPQRRAPHSHHLVIKSGELDLIDPHDLDVGGAAGAAEPSEGVGGDGKYVATF 
QGMGIIHTAKKFIAEELYKKLRKHRLCELNREPTEREEQQMQKEAAVMARTMNLNQVCLC 
FRAYRVEPGTGRWVPICEPVYSNPINNMKSALTGELKICRLSTTVSGVDGGEEVFMFVEK 
VCKNNIKIRFYELDEYDQEVWQEMAIFSEADVHHQYAIAFKTPPYRHKDITEPVEVLMQL 
FRPRDRCQSEPVLFKYKPRPGMMVVPGAGASGASRKRLRISSGNVSSEIPTVIQNDPNGP 
VGPAGVGGGGGGGGGGGGGGVIGSGSTTRLPPLHQPFPMLANHAGGGAIPEGQEPTSTTS 
LTTSAHHPDIMSGIGSTTTISKELTKASIIQEILNIPTTIASDVAFDSSDFPCNSEEFNK 
LIQEIGNQQDLVKLETDAETAGGGATDTESVLGRAIADLVASGDDSRQGEMLRKLLALIK 
LFAGDVNRSRQLLASHWTAANQQQLNCLHAAIRRNDTTIACKLIELLHEYQLAEELLDLP 
NDRNETGLHLAVSCNSEPIVKALLGAGAKLHYCDYRGNTPLHRAVVENVPDMVRLLLLQG 
GLRLDCTNDDGLTALQAAVYARNLKITRILLEAGASVREKDLKHGNNILHIAVDNDALDI 
VHYILEEVKEELGRERNNAGYTPLQLADAKSHTGQGNNKLIVRELLRHYPDGLQKEVKKE 
VDAAEDDEEEEEEEQEEEEDEDEEGGEEHGQREASAPSSSVLDSMDLINGERASIARLLE 
EHEPEAEPQRKATKRSDSGPDRTEPDTLLDEQCLEELCRLLDAGSGWRELGSLLDFHSFF 
TVWEQAPSPARMLLGYFEMQQLHLDRLIDMLRVLELRDPIRSIDEMICRRMK 

>Aaeg:REL1 Aaeg:N21441 AAEL007696 REL1 -REL1A Aa_REL1A 'REL1'
MGPNDNNVMEDDPSLPDLPNNLIVTDDILDLIIDIIDQEMPPTAQERPHVVITEQPQSKA 
LRFRYECEGRSAGSIPGVHSTPEQKTFPGIEIRGYKGRAVVVVSCVTKDPPYRPHPHNLV 
GKEGCKKGVCTVEINSSTMSYTFSNLGIQCVKKKDIEEALRLREEIRVDPFKTGYGHARQ 
PATIDLNAIRLCFQVFLEGQQRGRFTEPLQPVVSDVIYDKKAMSDLVICKLSDVTAPVAG 
GREIILLCEKVAKEDIAVRFYEEQHGNIVWEEYGEFQHTNVHKQVAICFRTPRYRTLEVE 
HPVMVNIQLKRPSDGATSEPLPFELTPLDSAKRKKRKPNTWGDTPEHMPEAARHPYYATL 
GNVPGEAIKTEPRDSPTHPFNFIGNYRQPNESPSPIERSPLYGNTTPVGQTSPYNAGRTS 
VTPTPGGYQPNVMNPDFLLGGTQQFQNQYAFPTLPPTNGQPMYLQQPQQQQQQQQFQPPA 
NMNNQQQFNVSNLIDPQDQLPQPGPSGVQAVPSFQPSGSIGEINISSPWLTMDSSELKSL 
MVHTLSDMKQEQQRIQQEAETLSDSFDRLSTNLNNLNKP 

>Aaeg:REL2 Aaeg:N21086 AAEL007624 REL2 Aa_REL2 'REL2'
MSTLLNLDSYRHELFEHHQHQQQHHQLQQLSSSPTYSVLSMESVSPVSSSSASPAADTSK 
YYASNSPSSVSNMSPKSTASDTSSFNMQNLNISNAYPYFAETHHQTMTTGEEGQLQTFTY 
NDPTQPRVELSVPQLTIVEQPVDKFRFRYQSEMHGTHGSLMGVHTEKSKKTFPTVQLHGF 
QGEAKIRCSLFQVDPNRRAAHSHNLVIKSGEIDLNDPHDIDVNEECNYVAMFQGMGIIHT 
AKKNIAEELSKKMKKQRSVEMNRELTLREEYQLQKEAAEMAKTMNLNQVCLCFQAFQVDA 
STGRWAQLCEPVYSNPINNMKSALTGELKICRLSATVGNVDGGEEVFMFVEKVCKNNIKI 
RFYELDEYDQEIWQDWGSFSEADVHHQYAIAFKTPAYHNKDITEPVEVLMQLYRPRDKCQ 
SEPVPFKFKPRFNISRKRPRVSSGLLSNEIPTVVPNEPGSSRLPSFHHPFSMMPPMQAPI 
AEASGSSSSHTISKEYNKSGIIQEILDSHIPTTIAGDISFSSNDFKEFVNCNSEELRKLI 
TEIGEAQEESKLETDAVSVGHVDEAAAQFERTLEQYLEHNSQAKDVEILKKILAIIRLLF 
RKNYDQCRELISALWMSANKLKANCLHMAIERRNITIACKLVELLQDHHLLDMLDLFNER 
NETALHLAVSANLVEVVDVLLLTGSRISYCDSRGNSALHRAVYENALDSLNVLLGHCKRN 
GFRLDSTNDDGFTALHLAVMCKNLKATKVLLDRGASYVLRDLKHGNNILHIAVESDSLDM 
VNFILEGVDKTLADEPNNAGYTPLQLANARHLANANNKLIVRELLRYNPSGVLEKEHLTE 
EEDDDQEQEENLPPSSDSQSETVLESMNVSCNRVEVIRLLEDYSPPNDEPKLTPLENVPY 
NSTLEDGSVYLFDEVCLSHLCGLLNRKNLWREVGSLLDFNSFFMIWETSVNPAGMLLNYF 
EMQKVKLEHLIDVLQALDQKEAIHYIDEMICRQMK 

>Aaeg:REL3 Aaeg:N18688 AAEL006930 -REL1B Aa_REL1B 'REL1'
MLSHNLSGKEEQTVQKMAQKPYVVITEQPQSKALRFRYECEGRSAGSIPGVSSTADHKTF 
PTIEVRGYTGRVVVVVSCVTKDPPYRPHPHNLVGKDGCKKGVCTVEINKSVMSYTFCSLG 
IQCVKKKDIKDALRLREEIRVDPFKTGYGHGRQPASIDLNAVRLCFQAFLEGPQQGHFTN 
PLVPVVSDIIYDKKAMSELVICKLSHVAAPMSGGKEVILLCEKVAKEDIAVRFYEEHQGK 
IVWEDQGEFQHSNVHKQVAISFRTPRYRSLDVDFPVMVHIQLQRPSDGATSEPVPFELIP 
VDGDNFCKKRKRSQFNSFELTEQNTRKDMQHAASMEPKERMIKIEPMDSHFQQQYTAQNA 
YRNPTESPDGNMTPMTAASPYEGAIGYQAGNEYYVVNHRYQSNYNNFSVGGPSNGYQQYH 
YQQTGVHYGMNNLAGASLPVNGQQGFNLQQQQSQMPDNLDCLLDMELAKGFPMNSSEIKT 
MIGQIEPQRMQQEEENLSNSFTKLTTNTTVNNMNK 

>Cpip:REL1 CPIJ012236 nuclear factor NF-kappa-B p105 subunit supercont3.366 57946 74029 Cp_REL2 'REL2'
MEQHLQQPLSSSPTYSVLSMESSASSSSPSAVSTASSNMSPKSTTSETSSFNMQNLNISA 
SFPYYDDGSSSQMQTYHFTTGHGNAADHPQIELSVPHLVILEQPVDKFRFRYQSEMHGTH 
GSLMGVHTEKSKKTFPSVELRGFQGEAKIRCSLFQVDPSKRAAHSHHLVIKSGEIDLIDP 
HDIEVNAETGYVAMFQGMGIIHTAKKNIAEELCKKIKRQRAVEMNREISLREEHQLQKEA 
VEMAKTMNLNQVCLCFQAFQVDPVSGMWQQLCEPVYSNAINNMKSALTGELKICRLSSTA 
GNIEGGEEVFMFVEKVCKNNIKIRFYELDEFDQEIWQDWGTFSEADVHHQYAIAFKTPPY 
RNKDITEPAEVLMQLFRPRDKCQSEPVPFKYKPRPGMLASASSSRKRQRVHSGNISSEIP 
TTVPNDGGLAAMTAVAATAGPSRLPALHQPFPMVTQSTISKEFNKSGIIQEILESNVQGH 
SGGPTGDITFNSGDFRDFIQCSSEDLHKLINEIGEAHEQSKLETDAVASGSGPAGGSHQE 
AVRLERALESYLEANRHDKDVEILRKILAIIKLFGRDYERCRELISALWMSSNKHKANCL 
HMAIERRESVISCKLVELLQEFQLHDLLGLVNDRNETALHLAVFSNQVAVVESLLLAGVR 
ISCCDYKGNSALHCAVVENCAESLDALVGHCKRNGLRWDTANDDGYSPLQLAVMCRNLRV 
TKLLLDRGASPTERDLKHGNNILHIAVESDSLDLVNYILEQVDKSLSDEPNNAGYTPLQL 
ANARHQVNASNKLIVRELLRFNPGGLLEKEPSNEDGDEDDEEAATQDDLSAPPVEAGSSE 
SVLLSMNLTCNRVEVIQLLENHVPTAAELTPLKTVPYGEGAGAVSELFDEPCLTELCELL 
NQNNVWKELGSLLDFNAFFSIWEMSPNPAEMLLSYFEMQKMKLDHLIDILQALEQKEAIH 
CIDEMITTFMGIEAGAKQQWMTYFRKPEGASSEGSMV 

>Cpip:REL3 CPIJ002469 embryonic polarity protein dorsal supercont3.32 1272249 1274910 Cp_REL1A 'REL1'
MPPTAPEKPYVVITEQPQSKALRFRYECEGRSAGSIPGVHSTPEQKTFPSIEVRGYKGRA 
VVVVSCVTKDPPYRPHPHNLVGKEGCKKGVCTVEINSASMSYTFSNLGIQCVKKKDIEEA 
LRLREEIRVDPFKTGYSHAKQPATIDLNAVRLCFQVFLEGQQRGRFTEPLQPVVSDVIYD 
KKAMSDLVICKLSDACASVAGGKEIILLCEKVAKEDISVRFYEEQHGHILWEDVGEFQHS 
NVHKQVAISFRTPRYRTLEIEQSVMVNIQLRRPSDGATSEPLPFELFPLDSGRRRFWSLQ 
KDILKNDSPENEVFKKILLEGSSGAVAPKKVLVPQQQQEDEVIVLLDTPLAEDKPIVAEQ 
MPSEQKTTEWIERNEFDDGDNSVNASVDNQLMDEGGSVEQQVPKEDEDKTLNELLEQVAE 
LDEIYEDHQLRRENMIFENELKNLEKSVPTGLIGNGGDKMDIDDVFDDAATYTSLQRAFK 
NPVSLALGPPVPPRPHNALELEPGVYDAVEPMLICPPSIEVSSLKRENKEDEKLPPLPPK 
RAKPNGSQNKENAIGDTGDEVILHSIIRKGSMRSLTPRPQSDQIIIMKSPDSPPNKKLPP 
TPPASPNKNEYGTLPKNKKPGFFSKLFSRKKSKSDLSASTTTLTQKDTPGASKEPSLANF 
EATETTRKNSEKHKAGKPVARSVSSVSCKRPSTDANPDVIYIPLKGDGPSTTNLTSRTGN 
GSGTHLSLPGNDSYERASTASLPPLDRKTVSALQLDVPIQDGNLELVAIADARSIKNLVE 
GDFGIKLDPSVDLTEAEHFALYTSIAPNAALSEFDETSCYYAPVEPGPLPQQPIRLNSNS 
YSADV 

>Cpip:REL4 CPIJ015741 transcription factor p65 supercont3.686 52912 54498 Cp_REL1B 'REL1'
MATPSQKPYVVITEQPQSKGLRFRYECEGRSAGSIPGVRSTTEHKTHPTIELRGYKGRAV 
VVVSCVTKDPPYRAHPHNLVGKDGCKEGVCTVVLNSATMSYTFNNLGIQCVKKKDIEGAL 
RTREKLRVDPYKTGFGHVKQLATIDLNAVRLCFQVFIEGQQPGRFSEPLQPVVSDVIYDK 
KAMSELVICKLSHVTAPTAGGKEIIILCEKVTKEDISVRFYEERDGRIVWEDVGEFQHNN 
VHKQVAICFRTPRYHTLETSQPVMVNIQLRRPSDGATSEPLPFELLPLDATGLSQKRKRP 
KFNSSEVLEQSHGGAPPAGSYGQMLPTVGEHVKLEPREQLFGFQGPYRNPNESPEHSPGI 
PNAYPDPNFPGPASTQPNDFFQQYPPNHYNYPPKPTQQYPNQQQFQPNFPMTQQPGPSTS 
TAPQPTCQQMAAAPGVPPQEYNLSSLLDMDIGRDFAMNSSEIKSIMGHFSTAASVAVPTE 
QQQQQYQQQVQTVQQQMVHRMHQDEEENLSNSFTRLTTNPMNDLNKLS 

>OFAS027043-PA Oncopeltus relish
MYIVHAVGGEESDLKIYENKKNWLESGSFHCPPSSSKVSFDTEELKQMDKNQSILLFQAFDAYTKEKICESVVSRKIKNLHNAETAALKITNYSLAKGSCRGNDEVFMLVEKISKDVEVNFFTIDKSSKKRMWEARAIYGPQHVHHQYAIVFKTPEYCNTNISSPVEVFVELYRKTDGARSEPVRFTYLPDDLCNLNVMLSEASQPKRLKEIVPDLTTLFENCDKDLSYLQLDELIDGEYLISSLEEDRILHPSCDLEFYNYEGLQPDIAELLENPSVQSDSGSCIEKEVHVKPHSRIRQSLFSGHDDLYASNSLIGKERPDRPKYYGEAQGEIRMIKTNFKHDLDRLRALYKILVCEPRIHTSLFVDVLKTYSKNGFDINTTDFVGNSIFLLACGHSREVVSHLLGFEKLNCDLMNLAGDNALHCASRGNKIDIVQDLIKHNFDPNAMNYKSGDTSLHIAVENNNMPLIKLLIENGADPLKNNFASVSPYDISASSENREIKSYIFAKAQESLKNKPFKISPSTYFVGDSEITSKIRSLKNKFHHLLQKTFVRRMILHVVIPVVICSTIYLFNLLL



